What is the molecular genetic basis of neurodevelopmental disorders?
Welcome to the Girirajan Lab website!
The primary focus of our research is to discover and characterize genetic changes including genomic deletions and duplications and single nucleotide mutations contributing to neurodevelopmental disorders such as autism, intellectual disability, schizophrenia, epilepsy and congenital malformation.

The Girirajan laboratory is affiliated to the following: Our lab combines experimental human genetics, functional genomics in model organisms, and computational genomics to understand the molecular etiology of neurodevelopmental disorders. We welcome applications from talented and committed individuals who are interested in studying human disease. Please send inquiries to sxg47 [at]

Recent news:

16p12.2 deletion recruitment

The Girirajan Lab is now recruiting patients and families carrying the 16p12.2 deletion for a study on the clinical variability associated with this disorder. If you are interested in participating, please fill out the questionairre here.

Disease-associated genes are routinely missed in some genetic studies

A project led by graduate student Qingyu Wang found 832 genes linked to diseases such as leukemia and heart failure have low coverage across multiple whole-exome sequencing platforms, suggesting the utility of whole-genome sequencing for these diseases. This study was recently published in Scientific Reports.